Recent advances in self interference suppression (SIS) allows a transmitting device to suppress its self-interference up to the noise floor, enabling two wireless radios to simultaneously transmit and receive on the same channel, using the same antenna array. Radios with this in-band full-duplex (IBFD) capability have the potential to not only double the network throughput but also helps solve various issues (e.g., Tx deafness, hidden/exposed nodes) at the MAC and network layers. Additionally, one can exploit the SIS capability in various applications like indoor localization, securing wireless transmissions. This talk gives an overview on recent developments of SIS and its implications on wireless networking and securities. Our latest findings on the network capacity and anti-jamming solutions for IBFD radios are presented.